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Malonic Ester Synthesis Reaction Mechanism + Ring Closing Example Substituted Carboxylic Acids |
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Written by punjalak
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Friday, 16 December 2016 15:20 |
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This video discusses the mechanism of the malonic ester synthesis reaction including an intramolecular ring closing example. After the removal of the alpha hydrogen, direct alkylation occurs with an alkyl bromide to an 1 or 2 R groups followed by acid hydrolysis to create two carboxylic acids. Decarboxylation occurs by the addition of heat creating a substituted Carboxylic Acid Derivative.
ที่มา : https://www.youtube.com/channel/UCEWpbFLzoYGPfuWUMFPSaoA
อัพโหลดโดย The Organic Chemistry Tutor
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